They propose to design a vaccine based on complexes that mimic the viral particles of SARS-CoV-2.
UAB researchers propose to design a vaccine based on complexes that mimic the viral particles of SARS-CoV-2. The initiative is part of a micro-patronage program against the University’s COVID-19, which also includes a FAS project in summer camps for the most vulnerable children and an action by the UAB Open Labs to manufacture protective material for to health personnel.
The UAB has launched a micro-patronage campaign to develop a SARS-CoV-2 coronavirus vaccine with a methodology that, as far as researchers know, is not being applied in any of the trials being carried out in Spain.
The initiative, which has already been launched, brings together the experience of different research groups, centers and scientific and technical services of the UAB, and has the collaboration of the Center for Research in Animal Health (CReSA) of the Agri-Food Research and Technology Institute (IRTA) and the Parc Taulí, Germans Trias, Vall d’Hebron and Santa Creu i Sant Pau hospitals, attached to the University, which will be responsible for validating the prototype generated.
The project “Ajuda’ns a desenvolupar una vacuna contra el SARS-COV-2” it is based on the design of recombinant proteins, which form nanostructures that mimic viral particles (virus-like particles or VLPs). These complexes do not have the genetic information of viruses and are therefore not infectious. The aim is to generate VLPs from the fragments of virus proteins that have SARS-CoV-2 antigens on their surface, so that they can induce the creation of neutralizing antibodies.
News published on 27/05/2020
